| Autor: |
Viviana Torres, Jesica Pérez‐Montesino, Rubén Fernández‐Santiago, Manel Fernández, Ana Camara, Yaroslau Compta, María‐José Martí, Àlex Guerra Beltran, José Rios, Francesc Valldeoriola, Mario Ezquerra |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Annals of Clinical and Translational Neurology, Vol 11, Iss 8, Pp 2222-2229 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2328-9503 |
| DOI: |
10.1002/acn3.52111 |
| Popis: |
Abstract Impulse control disorders and their consequences display variability among individuals, indicating potential involvement of environmental and genetic factors. In this retrospective study, we analyzed a cohort of Parkinson's disease patients treated with dopamine agonists and investigated the influence of the dopamine D4 receptor gene polymorphism, DRD4 7R+, which is linked to psychiatric disorders, impulsive traits, and addictive behaviors. We found that DRD4 7R+ is a significant genetic risk factor associated with the severity of ICD. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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