Patterns in progression from early-stage melanoma to late-stage melanoma: implications for survivorship follow-up
| Autor: | David J Savage, Benjamin Switzer, Rujul Parikh, Jung Min Song, Carolyn Stanek, Joshua Arbesman, Lucy Boyce Kennedy, Pauline Funchain |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Melanoma Management, Vol 11, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 20450885 2045-0893 2045-0885 |
| DOI: | 10.1080/20450885.2024.2424708 |
| Popis: | Aim: This study determined the characteristics of patients with early-stage melanoma (IA-IIA) who later had stage IV recurrence.Patients & methods: We retrospectively examined 880 melanoma patients and identified those who progressed to stage IV disease from an initial early-stage (n = 50).Results: We observed a median latent period of 4 years between early-stage diagnosis and metastatic disease. More patients (54%) developed metastatic disease 4 years or later from the initial diagnosis. 34% had regular dermatology appointments, and 30% had regular oncology follow-up. Lung and brain were the most common metastatic sites.Conclusion: Long term monitoring beyond 4 years and a low threshold for performing symptom-guided imaging, particularly if pulmonary or neurologic symptoms occur, may be prudent after early-stage melanoma diagnosis. |
| Databáze: | Directory of Open Access Journals |
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