Obesity and Insulin Resistance Components of Metabolic Syndrome Induced by High-fructose Diet in Wistar Rats could be attenuated by Spices-Supplemented Diets

Autor: N. U. Imam, A. S. Idoko, M. Osibemhe, N. Lawal, A. S. Zaharaddeen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Applied Sciences and Environmental Management, Vol 26, Iss 5 (2022)
Druh dokumentu: article
ISSN: 2659-1502
2659-1499
DOI: 10.4314/jasem.v26i5.17
Popis: Constant consumption of fructose-sweetened diets and beverages has led to increasing incidences of metabolic disorders such as metabolic syndrome (MS). This research was designed to evaluate the potentials of supplementing diets with some locally available spices in ameliorating obesity and insulin resistance in induced metabolic syndrome. Thirty out of thirty-five rats weighing 128.08±5.29g were induced with MS, divided into six groups and treated with diets supplemented with powders of garlic, ginger, turmeric, black pepper and equal mixture of the spices while the other 5 rats were maintained on normal diet throughout the experiment. The weight and blood glucose were recorded weekly, while serum insulin level was determined on the 56th day of the treatment after which HOMA-IR was computed. The group of MS-induced rats fed normal diet had significantly (p
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