| Autor: |
ZHOU Anqi |
| Jazyk: |
čínština |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
口腔疾病防治, Vol 29, Iss 5, Pp 334-339 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2096-1456 |
| DOI: |
10.12016/j.issn.2096-1456.2021.05.007 |
| Popis: |
Ideal osseointegration is intimately related to favorable osteoimmune properties around dental implants. An increasing number of in vitro and in vivo studies have indicated that the Hippo-YAP signaling pathway is involved in this biological process. In this article, the implicated roles of Hippo-YAP the signaling axis in peri-implant osteoimmunology were summarized by reviewing relevant evolving literature. The discrepancy concerning the Hippo-YAP signaling regulatory effect on osteogenesis and polarization direction were analyzed as well as propose the potential mechanism, which may be caused by the maturation of osteogenesis-related cells and heterogeneity of macrophages. More attention should be given to the requirements of promoting osteogenesis and patterns of regulating the immune microenvironment by Hippo-YAP in future studies. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
