| Autor: |
Victor Alves de Oliveira, Diego Cipriano Chagas, Jefferson Rodrigues Amorim, Renato de Oliveira Pereira, Thais Alves Nogueira, Victória Maria Luz Borges, Larysse Maira Campos-Verde, Luana Mota Martins, Gilmara Peres Rodrigues, Elmo de Jesus Nery Júnior, Fabiane Araújo Sampaio, Pedro Vitor Lopes-Costa, João Marcelo de Castro e Sousa, Vladmir Costa Silva, Felipe Cavalcanti Carneiro da Silva, Benedito Borges da Silva |
| Jazyk: |
angličtina |
| Předmět: |
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| Zdroj: |
Clinics |
| Druh dokumentu: |
article |
| ISSN: |
1980-5322 |
| DOI: |
10.6061/clinics/2020/e1762 |
| Popis: |
OBJECTIVE: This study aimed to determine the relationship between rs17576 (MMP-9) polymorphism and increased cancer risk in a Brazilian breast cancer cohort. METHODS: This study included 141 women (71 breast cancer patients and 70 controls without breast cancer) who donated 3 mL of their peripheral blood for genomic DNA extraction. This DNA was then genotyped using a real-time polymerase chain reaction. RESULTS: The AG (rs17576) genotype was identified in 26 (18.43%) participants in the case group and in 22 (15.60%) participants in the control group (p=0.274), while the GG genotype was identified in ten (7.09%) participants in the case group and in one (0.70%) participant in the control group (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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