PIONEER REAL Japan: Primary results from a multicenter, prospective, real‐world study of oral semaglutide in adults with type 2 diabetes in Japanese clinical practice

Autor:	Daisuke Yabe, Yoshiyuki Hamamoto, Daiji Kawanami, Rimei Nishimura, Yasuo Terauchi, Hanan Amadid, Uffe Christian Braae, Atheline Major‐Pedersen, Ryo Suzuki
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Diabetes mellitus type 2 Oral semaglutide Prospective studies Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Journal of Diabetes Investigation, Vol 15, Iss 11, Pp 1566-1577 (2024)
Druh dokumentu:	article
ISSN:	2040-1124 2040-1116
DOI:	10.1111/jdi.14291
Popis:	ABSTRACT Aims/Introduction PIONEER REAL Japan was a non‐interventional prospective study of oral semaglutide in adults with type 2 diabetes in Japanese clinical practice. Materials and Methods Adults naïve to injectable glucose‐lowering therapies initiated oral semaglutide in routine clinical practice and were followed for 34–44 weeks. The primary endpoint was change in glycated hemoglobin (HbA1c) from baseline to end of study; the co‐primary endpoint was number of adverse events (AEs). Secondary endpoints included change in bodyweight from baseline to end of study. Analyses were also carried out for subgroups aged
Databáze:	Directory of Open Access Journals
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