Novel Mutations in Obesity-related Genes in Turkish Children with Non-syndromic Early Onset Severe Obesity: A Multicentre Study
| Autor: | Ayşehan Akıncı, Doğa Türkkahraman, İbrahim Tekedereli, Leyla Özer, Bahri Evren, İbrahim Şahin, Tarkan Kalkan, Yusuf Çürek, Emine Çamtosun, Esra Döğer, Aysun Bideci, Ayla Güven, Erdal Eren, Özlem Sangün, Atilla Çayır, Pelin Bilir, Ayça Törel Ergür, Oya Ercan |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | JCRPE, Vol 11, Iss 4, Pp 341-349 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1308-5727 1308-5735 |
| DOI: | 10.4274/jcrpe.galenos.2019.2019.0021 |
| Popis: | Objective:Non syndromic monogenic obesity is a rare cause of early onset severe obesity in the childhood period. This form may not be distinguishable from other forms of severe obesity without genetic analysis, particularly if patients do not exibit any physical abnormalities or developmental delay. The aim of this study was to screen 41 different obesity-related genes in children with non-syndromic early onset severe obesity.Methods:Children with severe (body mass index-standard deviation score >3) and early onset ( |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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