Supra-Therapeutic Selective Serotonin Reuptake Inhibitor (Ssri) Dosesfor Refractory Obsessive-Compulsive Disorder: A Case Report
| Autor: | Syed Faraz Zafar, Michelle Ahmed |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Pakistan Armed Forces Medical Journal, Vol 74, Iss 2 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0030-9648 2411-8842 54282098 |
| DOI: | 10.51253/pafmj.v74i2.6881 |
| Popis: | response to standard first-line treatments. We report a case of treatment-refractory OCD that was successfully treated with the pharmacological strategy of using selective serotonin reuptake inhibitors (SSRIs) in the above-licensed doses. Patient, a 26-year-old male, had failed to respond to multiple trials of SSRIs inside the licensed dose range and augmentation with antipsychotic medication when he was started on high-dose escitalopram(40mg/day). His clinical condition improved greatly after 12 weeks on this regimen, as demonstrated by a significant decrease in the Yale-Brown Obsessive Compulsive Scale (from 33 to 12). This case provides additional support to a small body of evidence that suggests the utility of using higher doses of selective serotonin reuptake inhibitors (SSRIs) in treatment-resistant obsessive-compulsive disorder (OCD). |
| Databáze: | Directory of Open Access Journals |
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