Paraneoplastic syndromes in neuro-ophthalmology

Autor:	Simon J Hickman
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	cancer immunomodulation neuro-ophthalmology paraneoplastic autoantibodies paraneoplastic neurological syndrome Neurology. Diseases of the nervous system RC346-429
Zdroj:	Annals of Indian Academy of Neurology, Vol 25, Iss 8, Pp 101-105 (2022)
Druh dokumentu:	article
ISSN:	0972-2327 1998-3549
DOI:	10.4103/aian.aian_102_22
Popis:	Paraneoplastic neurological syndromes (PNS) occur in about 1 in 300 cases of cancer. The usual mechanism is that an antigen on the cancer sets off an immune response that then cross-reacts with a nervous system antigen. The presentation is usually with a subacute progressive neurological disorder. The management of these conditions is usually of both the underlying tumor and immunomodulation to suppress the autoimmune response. There are a number of these conditions that can present to the Neuro-Ophthalmology clinic, either as a discrete condition affecting vision or eye movements or as part of a more widespread neurological disorder. This article will discuss these conditions, their management and prognosis.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/bec256c294104cab826d3a1eb726b97c Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF