Metastatic Renal Cell Carcinoma in Nasopharynx-A Paradox: Case Report and Review of Literature

Autor: Kachnar Varma, Faheema Hasan, Vatsala Misra, PA Singh
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 12, Iss 7, Pp ED01-ED03 (2018)
Druh dokumentu: article
ISSN: 2249-782X
0973-709X
DOI: 10.7860/JCDR/2018/29478.11713
Popis: Metastatic renal cell carcinoma of the head and neck is extremely rare. Metastasis to the nasopharynx is extremely unusual and can be misdiagnosed as primary of the specific site hindering further management. The present case report of an 82-year-old male presenting with epistaxis was found to have a nasopharyngeal mass on radiology. Microscopic evaluation of the nasopharyngeal mass revealed a highly vascular clear cell tumour with cells arranged in alveolar and trabecular pattern. Immunohistochemical assessment revealed positive PAX 8, CD10 and vimentin which are highly specific for metastatic renal cell carcinoma. Retrospective computed tomography scan revealed a renal mass; however, the patient succumbed before any biopsy could be performed.
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