Establishment and validation of prognostic nomogram in acute leukemia with trisomy 8

Autor:	Tianxia Deng, Sheng Wang, Zhuonan Ran, Qiulian Liu, Mingxia Wang
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Trisomy 8 acute leukemia prognosis nomogram validation aged Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Hematology, Vol 28, Iss 1 (2023)
Druh dokumentu:	article
ISSN:	16078454 1607-8454
DOI:	10.1080/16078454.2023.2240131
Popis:	ABSTRACTObjective This study aims to construct a nomogram model for predicting poor prognosis in acute leukemia with trisomy 8.Methods A retrospective analysis was conducted on 244 patients with primary acute leukemia with trisomy 8 who received treatment in our hospital, and they were randomly divided into the modeling group (122 cases, including 78 cases with good prognosis and 44 cases with poor prognosis) and the verification group (122 cases). R software was used to construct a nomogram model for predicting poor prognosis in acute leukemia with trisomy 8.Results The results of multivariate analysis showed that age >51 years old, and white blood cell count ≤20 × 109/L were risk factors for poor prognosis in acute leukemia patients with trisomy 8 (P
Databáze:	Directory of Open Access Journals
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