Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3

Autor: Ji-De Wang, Chen-Jiang Liu
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Molecules, Vol 15, Iss 4, Pp 2087-2095 (2010)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules15042087
Popis: An efficient synthesis of novel 4-(2-phenyl-1,2,3-triazol-4-yl)-3,4-dihydro-pyrimidin-2(1H)-(thio)ones from 1,3-dicarbonyl compounds, 2-phenyl-1,2,3-triazole-4-carbaldehyde and urea or thiourea under ultrasound irradiation and using samarium perchlorate as catalyst is described. Compared with conventional methods, the main advantages of the present methodology are milder conditions, shorter reaction times and higher yields.
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