Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers

Autor: Andréa Pinto Leite Ribeiro, Beatriz Guitton Renaud Baptista de Oliveira, Marja Ferreira Soares, Bruna Maiara Ferreira Barreto, Débora Omena Futuro, Selma Rodrigues de Castilho
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Předmět:
Zdroj: Revista da Escola de Enfermagem da USP, Vol 49, Iss 3, Pp 394-400
Druh dokumentu: article
ISSN: 1980-220X
0080-6234
DOI: 10.1590/S0080-623420150000300006
Popis: OBJECTIVE To analyze the effectiveness of 2% and 4% papain gels in tissue repair of venous ulcers. METHOD Quasi-experimental study with consecutive sample of 16 patients with 30 venous ulcers treated at the outpatient clinic of a teaching hospital, from April to November in 2011, using a form for clinical assessment of the patient and its lesion. Variables were analyzed by Wilcoxon and McNemar test (p < 0.05). RESULTS Most participants were female; aged between 51 and 59 years; obese; with hypertension. Regarding ulcers, there was an average decrease of 7.9 cm2 (50% of its original size) in 90 days; 20% of the ulcers completely healed within 56.67 days. There was an increase in epithelialization, significant reduction in the slough and edema, improved depth, in the type and amount of exudate (p < 0.0001). CONCLUSION 2% and 4% papain gels were effective in healing venous ulcers.
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