A case of chronic pruritus developing at a noninjured nerve area in a patient with spinal cord injury: Role of protein gene product 9.5

Autor:	Akimasa Adachi, Mayumi Komine, Satoru Murata, Mamitaro Ohtsuki
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	nerve injury PGP9.5 pruritus spinal cord injury urticaria Dermatology RL1-803 Diseases of the genitourinary system. Urology RC870-923
Zdroj:	JEADV Clinical Practice, Vol 3, Iss 4, Pp 1215-1218 (2024)
Druh dokumentu:	article
ISSN:	2768-6566
DOI:	10.1002/jvc2.360
Popis:	Abstract A patient in her 60s with spinal cord injury developed pruriginous lesion only in a nerve‐noninjured area, although erythema resulting from scratching was also prominent in a nerve‐injured lesion. The area of protein gene product 9.5 (PGP9.5)‐positive nerve fibres within the nerve‐injured lesion was significantly reduced compared with the nerve‐noninjured area. This case suggests an essential role for PGP 9.5‐positive nerve fibres in the development of chronic pruritus.
Databáze:	Directory of Open Access Journals
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