Use of a Longer Aglycon Moiety Bearing Sialyl α(2→3) Lactoside on the Glycopolymer for Lectin Evaluation

Autor:	Ryota Adachi, Takahiko Matsushita, Tetsuo Koyama, Ken Hatano, Koji Matsuoka
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	glycopolymers radical polymerizations carbohydrates glycosides oligosaccharides glycoclusters Organic chemistry QD241-441
Zdroj:	Polymers, Vol 15, Iss 4, p 998 (2023)
Druh dokumentu:	article
ISSN:	2073-4360
DOI:	10.3390/polym15040998
Popis:	A polymerizable alcohol having 9 PEG repeats was prepared in order to mimic an oligosaccharide moiety. Sialyl α(2→3) lactose, which is known as a sugar moiety of GM3 ganglioside, was also prepared, and the polymerizable alcohol was condensed with the sialyl α(2→3) lactose derivative to afford the desired glycomonomer, which was further polymerized with or without acrylamide to give water-soluble glycopolymers. The glycopolymers had higher affinities than those of glycopolymers having sialyl lactose moieties with shorter aglycon moieties.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ebe739cbfd1540e1b46b3a8c9c844ac0 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.