VARIAÇÕES PLASMÁTICAS DE AMINAS VASOATIVAS EM EQUINOS SOB EFEITO DE SOBRECARGA DE CARBOIDRATOS E ANTI-INFLAMATÓRIOS NÃO ESTEROIDAIS

Autor: Renata Sampaio Costa, Paulo de Tarso Landgraf Botteon, Vany Perpétua Ferraz, Fabíola de Oliveira Paes Leme, Rafael Resende Faleiros, Geraldo Eleno Silveira Alves
Jazyk: English<br />Portuguese
Rok vydání: 2012
Předmět:
Zdroj: Ciência Animal Brasileira, Vol 13, Iss 1, Pp 93-98 (2012)
Druh dokumentu: article
ISSN: 1518-2797
Popis: Twenty horses were submitted to carbohydrate overload (CO) and plasmatic concentrations of the bioactive amine serotonin (5-HT), putrescin (PUT) and cadaverin (CAD) were determined by gas chromatography. After 36h of carbohydrate overloading, horses were randomly distributed into four groups (n=5) and were submitted to four intravenous treatments every 12 hours. The treatments were as follows: 10ml of saline (GC), ketoprofen 2.2mg/kg (GK), phenylbutazone 4.4mg/kg (GF), and flunixin meglumine 1.1mg/kg (GFM). Blood samples were collected at regular intervals (0-72h) after the CO. After 6h, there were peaks in the concentrations of 5-HT, which rapidly returned to values above the basal standard. No variations of PUT concentrations were observed; however CAD concentrations increased at 6h, remaining elevated (with some variation) until the end of the observation period. In conclusion, CO induced early (6h) increases in plasmatic concentrations of 5-HT and CAD. Plasmatic concentrations of the amines were not changed by any of the treatments used.
Databáze: Directory of Open Access Journals