| Autor: |
Alessandra Prioreschi, John R. Koethe, David M. Aronoff, Jeffrey A. Goldstein, Shane A. Norris |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Obesity Science & Practice, Vol 8, Iss 4, Pp 500-509 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2055-2238 |
| DOI: |
10.1002/osp4.570 |
| Popis: |
Abstract Objective Adipose tissue is a central regulator of metabolic health and a contributor to systemic inflammation. Patterns of adiposity deposition are important to understand for optimizing health. This study aimed to asses relationships between adiposity deposition and metabolic and inflammatory biomarkers in South African women prior to conception. Methods Non‐pregnant, healthy women (n = 298) were recruited for this cross‐sectional study via home visits. Body composition was measured by Dual X‐ray Absorptiometry. Inflammation markers C‐reactive protein (CRP), alpha1‐acid glycoprotein (AGP), hemoglobin A1c (HbA1c), and blood pressure were scored according to risk. A summative metabolic health risk score was created for women with obesity. Generalized regression models assessed relationships between adiposity deposition and outcomes with adjustment for potential confounders. Results Obesity was present in 22% of women (mean age = 20.93 years). Fat mass index was associated with inflammation and metabolic health risk (β = 0.58; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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