Effects of Chitosan/Nano Selenium Biofilm on Infected Wound Healing in Rats; An Experimental Study
| Autor: | Abolfazl Abbaszadeh, Akram Tehmasebi-Foolad, Asghar Rajabzadeh, Nasim Beigi-Brojeni, Leila Zarei |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Bulletin of Emergency and Trauma, Vol 7, Iss Issue 3, Pp 284-291 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2322-2522 2322-3960 |
| DOI: | 10.29252/beat-0703012 |
| Popis: | Objective: The present study was aimed at assessment of effect of application of Chitosan/Nano Selenium biofilm on infected wound healing in ratsMethods: Sixty-eight male Wistar rats were randomized into four groups of 17 animals each. In group I (Normal) the wounds were created with no infection. In group II (MRSA), the wounds were infected with methicillin resistant Staphylococcus aureus (MRSA). In group III (MRSA/CHIT), animals with infected wounds were dressed with chitosan biofilm only. In group IV (MRSA/CHIT/NS), animals with infected wounds were dressed with Chitosan/Nano Selenium biofilm.Results: There were significant differences in comparisons of group IV and other groups, particularly in terms of cellular infiltration and neovascularization. During the study period, scores for neovascularization was significantly higher in group IV rats than other groups (P |
| Databáze: | Directory of Open Access Journals |
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