Hemodynamic Patterns Identified by Impedance Cardiography Predict Mortality in the General Population: The PREVENCION Study

Autor: Josefina Medina‐Lezama, Offdan Narvaez‐Guerra, Karela Herrera‐Enriquez, Oscar L. Morey‐Vargas, Juan Francisco Bolaños‐Salazar, Juan P. Abugattas, Humberto Zea‐Diaz, Jose L. Chirinos‐Revilla, Jenny G. Fernandez‐Sivincha, Victor Delgado‐Lazo, Diana A. Chirinos, Raymond R. Townsend, Julio A. Chirinos
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 18 (2018)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.118.009259
Popis: Background Blood pressure is determined by the interactions between the heart and arterial properties, and subjects with identical blood pressure may have substantially different hemodynamic determinants. Whether arterial hemodynamic indices quantified by impedance cardiography (ICG), a simple operator‐independent office procedure, independently predict all‐cause mortality in adults from the general population, and specifically among those who do not meet criteria for American College of Cardiology/American Heart Association stage 2 hypertension, is currently unknown. Methods and Results We studied 1639 adults aged 18 to 80 years from the general population. We used ICG to measure hemodynamic parameters and metrics of cardiac function. We assessed the relationship between hemodynamic parameters measured at baseline and all‐cause mortality over a mean follow‐up of 10.9 years. Several ICG parameters predicted death. The strongest predictors were total arterial compliance index (standardized hazard ratio=0.38; 95% confidence interval=0.31–0.46; P
Databáze: Directory of Open Access Journals