A case of vascularized corneal opacity treated with aflibercept

Autor: A.S. Cholak, I.O. Nasinnyk, P.O. Kostenko, S.A. Iakimenko, A.R. Korol
Jazyk: English<br />Ukrainian
Rok vydání: 2020
Předmět:
Zdroj: Journal of Ophthalmology, Iss 1, Pp 54-56 (2020)
Druh dokumentu: article
ISSN: 2412-8740
DOI: 10.31288/oftalmolzh202015456
Popis: Background: Corneal neovascularization (CNV) is a serious condition that can lead to a profound decline in vision. Current research on treating CNV with angiogenesis inhibitors is underway in numerous centers, and a number of studies have demonstrated the efficacy of this approach. Purpose: To present a case of corneal neovascularization treated with aflibercept. Material and Methods: An ocular examination included visual acuity assessment, biomicroscopy, anterior eye photography and fluorescein angiography (FA). In addition, an area of CNV was assessed before and 6 months after a single subconjunctival injection of 4 mg (0.1ml) aflibercept. Results: An area of CNV decreased from 38,081 pixels before injection to 20,782 at 6 months, with a reduction in 17,299 pixels. Conclusion: In the case reported here, a single subconjunctival injection of 4 mg (0.1ml) aflibercept was found to be effective for reducing corneal neovascularization at 6 weeks.
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