Blastic Plasmacytoid Dendritic Cell Neoplasm with Lung Involvement and Cytopenia: A Case Report and a Literature Review

Autor: Liu F, Qi F, Zhang J, Tan Y, Zhang X
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinical, Cosmetic and Investigational Dermatology, Vol Volume 16, Pp 2211-2216 (2023)
Druh dokumentu: article
ISSN: 1178-7015
Popis: Fang Liu,1 Fei Qi,2 Jingya Zhang,1 Yaqi Tan,1 Xiuying Zhang1 1Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Dermatology, Peking Union Medical College Hospital, Beijing, People’s Republic of ChinaCorrespondence: Fang Liu, Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, 8 Gongti South Road, Chaoyang District, Beijing, 100020, People’s Republic of China, Tel +86-10-85231688, Fax +86-10-85231217, Email roseliufang@qq.comAbstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a hostile cutaneous malignancy with dismal prognosis and unknown etiology with rarity. Most patients received traditional chemotherapy only has one year of median survival time. This article reports an 81-year-old male patient with BPDCN who presented with skin manifestations and was diagnosed with positive CD4, CD56, and CD123 immunohistochemical results. Systematic examination revealed lung involvement and cytopenia.Keywords: blastic plasmacytoid dendritic cell neoplasm, pathological feature, lung involvement, cytopenia, treatment, prognosis
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