Long-term survival in glioblastoma: methyl guanine methyl transferase (MGMT) promoter methylation as independent favourable prognostic factor

Autor: Smrdel Uros, Popovic Mara, Zwitter Matjaz, Bostjancic Emanuela, Zupan Andrej, Kovac Viljem, Glavac Damjan, Bokal Drago, Jerebic Janja
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Radiology and Oncology, Vol 50, Iss 4, Pp 394-401 (2016)
Druh dokumentu: article
ISSN: 1581-3207
DOI: 10.1515/raon-2015-0041
Popis: In spite of significant improvement after multi-modality treatment, prognosis of most patients with glioblastoma remains poor. Standard clinical prognostic factors (age, gender, extent of surgery and performance status) do not clearly predict long-term survival. The aim of this case-control study was to evaluate immuno-histochemical and genetic characteristics of the tumour as additional prognostic factors in glioblastoma.
Databáze: Directory of Open Access Journals