Bacteremia after Bacillus clausii administration for the treatment of acute diarrhea: A case report

Autor: Juan Pablo García, Julián Andrés Hoyos, John Alexander Alzate, Edilberto Cristancho
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2021
Předmět:
Zdroj: Biomédica: revista del Instituto Nacional de Salud, Vol 41, Iss Sp. 2, Pp 13-20 (2021)
Druh dokumentu: article
ISSN: 0120-4157
DOI: 10.7705/biomedica.5662
Popis: Bacillus clausii is a gram-positive rod used as a probiotic to treat diarrhea and the side effects of antibiotics such as pseudomembranous colitis. We report a case of B. clausii bacteremia in a non-immunocompromised patient with active peptic ulcer disease and acute diarrhea. The probiotic was administered during the patient´s hospitalization due to diarrhea of infectious origin. B. clausii was identified in the bloodstream of the patient through Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) days after her discharge. Given the wide use of probiotics, we alert clinicians to consider this microorganism as a causative agent when signs of systemic infection, metabolic compromise, and hemodynamic instability establish after its administration and no pathogens have been identified that could explain the clinical course.
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