Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling

Autor: Joseph D. Challenger, Katia Bruxvoort, Azra C. Ghani, Lucy C. Okell
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-01352-3
Popis: Artemether lumefantrine is widely used for the treatment of uncomplicated malaria. The impact of imperfect patient adherence to the six-dose regimen is hard to assess. Using adherence data for unsupervised patients, the authors model how suboptimal adherence affects treatment outcomes.
Databáze: Directory of Open Access Journals