The application of vicasole as a perspective nephrolithyiasis pharmacological correction’s drug

Autor: A. Yu. Zharikov, Ya. F. Zverev, V. V. Lampatov, V. M. Bryukhanov, O. V. Azarova, O. S. Talalayeva, Yu. G. Motin
Jazyk: English<br />Russian
Rok vydání: 2012
Předmět:
Zdroj: Бюллетень сибирской медицины, Vol 11, Iss 1, Pp 18-24 (2012)
Druh dokumentu: article
ISSN: 1682-0363
1819-3684
DOI: 10.20538/1682-0363-2012-1-18-24
Popis: The aim of the investigation was studying vicasole’s effect on experimental oxalate nephrolithiasis.Experimental nephrolithiasis was being modeled by using of 1% ethylenglycole’s solution as a drink for rats during 6 weeks. First group was control. In the second group since the third week was being administrated vicasole in dose 500 mkg/kg. Was being detected parameters of kidney’s function, markers enzymes activity and free oxygen’s radicals activity, was carried out morphological researches.It was concluded that vicasole’s therapy reduce experimental oxalate nephrolithiasis
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