Real time monitoring of respiratory viral infections in cohort studies using a smartphone app

Autor: David G. Hancock, Elizabeth Kicic-Starcevich, Thijs Sondag, Rael Rivers, Kate McGee, Yuliya V. Karpievitch, Nina D’Vaz, Patricia Agudelo-Romero, Jose A. Caparros-Martin, Thomas Iosifidis, Anthony Kicic, Stephen M. Stick
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: iScience, Vol 27, Iss 10, Pp 110912- (2024)
Druh dokumentu: article
ISSN: 2589-0042
DOI: 10.1016/j.isci.2024.110912
Popis: Summary: Cohort studies investigating respiratory disease pathogenesis aim to pair mechanistic investigations with longitudinal virus detection but are limited by the burden of methods tracking illness over time. In this study, we explored the utility of a purpose-built AERIAL TempTracker smartphone app to assess real-time data collection and adherence monitoring and overall burden to participants, while identifying symptomatic respiratory illnesses in two birth cohort studies. We observed strong adherence with daily app usage over the six-month study period, with positive feedback from participant families. A total of 648 symptomatic respiratory illness events were identified with significant variability between individuals in the frequency, duration, and virus detected. Collectively, our data show that a smartphone app provides a reliable method to capture the longitudinal virus data in cohort studies which facilitates the understanding of early life infections in chronic respiratory disease development.
Databáze: Directory of Open Access Journals