The relationship between serotonine, histamine and the brain`s electrical activity in patients with depression and endocrine disorders
| Autor: | Oana-Maria Nicola (Marioara), Alice Elena Ghenea, Cristina-Nicoleta Vlădoianu, Mara Carsote, Mihaela Popescu |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Romanian Medical Journal, Vol 68, Iss 2, Pp 273-277 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1220-5478 2069-606X |
| DOI: | 10.37897/RMJ.2021.2.22 |
| Popis: | Introduction. Depression is a persistent mental state of sadness that can affect an individual`s thoughts, behavior, emotion and well-being. The electroencephalogram (EEG) is of great importance both for experimental neurophysiology and for clinical diagnosis. The purpose of our study was to establish if there is a connection between the values of serotonine, histamine and EEG in patients with depression and endocrine pathology based on the collected data. Materials and methods. We included 50 individuals diagnosed with depression from Endocrinology Clinic of Craiova, over a period of 2 years (2018-2020). Serotonine and histamine were measured in blood and urine/24 hours in all the sample. Electroencephalography was performed to this patients. Outcomes. In our study, 27 patients had mild depression, 17 had moderate depression and 6 had a severe disorder. Also, the serotonine values were low (normal value 80-400 μg/L) in patients with depression and endocrine pathology. Conclusion. In patients with EEG abnormalities occure significant changes in the values of serotonine and histamine (increased urinary histamine and decreased serotonine levels). |
| Databáze: | Directory of Open Access Journals |
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