Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues

Autor: Andrew R. Marderstein, Manik Uppal, Akanksha Verma, Bhavneet Bhinder, Zakieh Tayyebi, Jason Mezey, Andrew G. Clark, Olivier Elemento
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-16097-9
Popis: Immune infiltration provides critical information for health and disease, yet it is unclear what factors influence infiltration levels. Here, the authors analyze human tissue transcriptomes from the Genotype-Tissue Expression project to find infiltration patterns regulated by age, sex and host genetic information.
Databáze: Directory of Open Access Journals