| Autor: |
Hailye Birhane, Mathew George, Lincy Joseph, Mujahidu Islam, Damen H/Mariam, Vijender Singh |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Songklanakarin Journal of Science and Technology (SJST), Vol 44, Iss 2, Pp 415-420 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
0125-3395 |
| DOI: |
10.14456/sjst-psu.2022.58 |
| Popis: |
Antibiotics are one of the most common drugs that can induce adverse drug reaction (ADR). A retrospective analysis was conducted using suspected antibiotic-related ADR data collected from the Ethiopian Pharmacovigilance Center over a 5-year period (2014-2019). There were a relatively large number of antibiotic-related ADRs (57.9%) containing 462 suspected drugs reported, with adults aged 18-64 (65.5%) and females (61.5%) predominating in the reported cases. Monotherapy and oral route administration were responsible for 85% and 83% of ADRs, respectively. Co-trimoxazole and amoxicillin were responsible for more than half of the reported ADRs and skin disorder was half of the affected system organ (SOC). Serious ADRs constituted 26% of all reported ADRs. The outcome of the patient showed that (44.7%) of patients were completely recovered after discontinuing the offending drug and additional intervention. The finding in this study suggests that antibiotic related ADRs are a significant health problem for patients in Ethiopia and further health facility based research is suggested. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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