False-positive rapid diagnostic test for malaria in new world cutaneous leishmaniasis: a tale of two travelers
| Autor: | Rebecca Unterborn, Jose Henao-Cordero, Arianna Kousari, Poornima Ramanan, Carlos Franco-Paredes, Nancy Madinger |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Therapeutic Advances in Infectious Disease, Vol 9 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2049-937X 20499361 |
| DOI: | 10.1177/20499361221097791 |
| Popis: | We report two immigrants from Cuba seen in a US travel clinic with a confirmed diagnosis of cutaneous leishmaniasis in whom we also suspected malaria co-infection. Both individuals likely acquired leishmaniasis in the Darien Gap region of Panama during their migratory path to the United States. As part of their clinical workup to rule out malaria, a rapid malaria antigen testing for P. falciparum was obtained and reported positive in both patients, However, both a qualitative reverse transcription-polymerase chain reaction (RT-PCR) for Plasmodium falciparum in blood and repeated thick-and-thin smear direct microscopy were negative in both, deeming the rapid malaria test as a false-positive. Thus, confirmation of malaria in travelers requires thick-and-thin film microscopy. Clinicians should be aware of the growing recognition of the possibility of false-positive malaria rapid diagnostic tests in those with some forms of leishmaniasis |
| Databáze: | Directory of Open Access Journals |
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