Hospitalization rates and resource utilization of schizophrenic patients switched from oral antipsychotics to aripiprazole-depot in Germany

Autor: Christoph Potempa, Reinhard Rychlik
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Health Economics Review, Vol 8, Iss 1, Pp 1-11 (2018)
Druh dokumentu: article
ISSN: 2191-1991
DOI: 10.1186/s13561-018-0215-5
Popis: Abstract Objective Examine cost-driving factors of schizophrenia in Germany for patients prior- and post-switch from an oral antipsychotic therapy to aripiprazole-depot and perform a budget impact analysis (BIA) referring to the context of German health care. Methods A single-armed, retrospective, non-interventional pre-post comparison study with 132 patients to compare the total psychiatric hospitalization rates and the associated costs of both, the treatment with oral antipsychotics and aripiprazole-depot. The BIA was performed to compare both treatment periods with respect to health-related costs. A subsequent univariate sensitivity analysis examined the robustness of the results. Results After switching the treatment to aripiprazole-depot, the total psychiatric hospitalization rates for the 6-month treatment period were significantly (p
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