Airway nitrite is increased in extremely preterm infants with bronchopulmonary dysplasia

Autor: Samuel J. Gentle, Amelia Freeman, Rakesh P. Patel, Namasivayam Ambalavanan, Charitharth V. Lal
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Respiratory Research, Vol 21, Iss 1, Pp 1-4 (2020)
Druh dokumentu: article
ISSN: 1465-993X
DOI: 10.1186/s12931-020-01508-8
Popis: Abstract Rationale Bronchopulmonary dysplasia (BPD) is the most common complication of prematurity and significantly contributes to mortality and morbidity with few predictive biomarkers. Given that nitrites have been implicated in pathways associated with lung disease, we hypothesized that nitrite levels would be altered in the airways of premature infants diagnosed with BPD. Methods This was a prospective cohort study of extremely low birth infants (
Databáze: Directory of Open Access Journals
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