Mechanism of glycogen synthase inactivation and interaction with glycogenin

Autor: Laura Marr, Dipsikha Biswas, Leonard A. Daly, Christopher Browning, Sarah C. M. Vial, Daniel P. Maskell, Catherine Hudson, Jay A. Bertrand, John Pollard, Neil A. Ranson, Heena Khatter, Claire E. Eyers, Kei Sakamoto, Elton Zeqiraj
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-31109-6
Popis: Glycogen is a major energy reserve in eukaryotes and is synthesised in part by glycogenin (GN) and glycogen synthase (GS). Here, authors describe the structural basis of GS regulation, specifically the mechanism of inactivation by phosphorylation.
Databáze: Directory of Open Access Journals