Chronic lymphocytic leukemia in the elderly: clinico-biological features, outcomes, and proposal of a prognostic model
| Autor: | Tycho Baumann, Julio Delgado, Rodrigo Santacruz, Alejandra Martínez-Trillos, Cristina Royo, Alba Navarro, Magda Pinyol, María Rozman, Arturo Pereira, Neus Villamor, Marta Aymerich, Cristina López, Anna Carrió, Emili Montserrat |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Haematologica, Vol 99, Iss 10 (2014) |
| Druh dokumentu: | article |
| ISSN: | 0390-6078 1592-8721 |
| DOI: | 10.3324/haematol.2014.107326 |
| Popis: | We investigated the clinico-biological features, outcomes, and prognosis of 949 patients with chronic lymphocytic leukemia according to age. No biological differences (cytogenetics by fluorescent in situ hybridization, IGHV, ZAP-70, CD38, NOTCH1, SF3B1) were found across age groups. Elderly patients (>70 years; n=367) presented more frequently with advanced disease (Binet C/Rai III-IV: 10/12% versus 5/5%; P |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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