| Autor: |
Min Wang, Hongyu Chen, Yue Ma, Ruobing Bai, Sizhe Gao, Linlin Yang, Wenli Guo, Cong Zhang, Chengjun Kang, Yu Lan, Yanqiu Sun, Yonggao Zhang, Xigang Xiao, Yang Hou |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Insights into Imaging, Vol 15, Iss 1, Pp 1-11 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1869-4101 |
| DOI: |
10.1186/s13244-024-01716-6 |
| Popis: |
Abstract Objectives To evaluate the diagnostic accuracy of liver dual-layer spectral-detector CT (SDCT) derived parameters of liver parenchyma for grading steatosis with reference to magnetic resonance imaging-based proton density fat fraction (MRI-PDFF). Methods Altogether, 320 consecutive subjects who underwent MRI-PDFF and liver SDCT examinations were recruited and prospectively enrolled from four Chinese hospital centers. Participants were classified into normal (n = 152), mild steatosis (n = 110), and moderate/severe(mod/sev) steatosis (n = 58) groups based on MRI-PDFF. SDCT liver parameters were evaluated using conventional polychromatic CT images (CTpoly), virtual mono-energetic images at 40 keV (CT40kev), the slope of the spectral attenuation curve (λ), the effective atomic number (Zeff), and liver to spleen attenuation ratio (L/S ratio). Linearity between SDCT liver parameters and MRI-PDFF was examined using Spearman correlation. Cutoff values for SDCT liver parameters in determining steatosis grades were identified using the area under the receiver-operating characteristic curve analyses. Results SDCT liver parameters demonstrated a strong correlation with PDFF, particularly Zeff (rs = −0.856; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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