Mean platelet volume predicts the glycemic control deterioration in diabetes mellitus type 2 patients

Autor: Damira Kadić, Sabaheta Hasić, Emina Spahić
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Medicinski Glasnik, Vol 13, Iss 1, Pp 1-7 (2016)
Druh dokumentu: article
ISSN: 1840-0132
1840-2445
DOI: 10.17392/843-16
Popis: Aim To investigate association of mean platelet volume (MPV) and glycemic control markers, and whether MPV could be used as a predictor of deterioration of glucoregulation in Diabetes mellitus type 2 (DMT2) patients. Methods The cross-sectional study included 106 DMT2 patients, treated at the Primary Health Care Centre in Zenica, distributed into groups according to glycated haemoglobin (HbA1c) values: A (n=44, HbA1c ≤7.0%) and B (n=62, HbA1c>7.0%). Spearman’s correlation coefficients were calculated to evaluate the relationships between MPV and glycemic control markers. Binomial logisticregression analysis was performed to estimate the relationship between glycemic control, as dichotomous outcome, and MPV as the main predictor. Diagnostic value of MPV as a marker for poor glucoregulation was estimated by using ROC analysis. Results Mean platelet volume was significantly higher in the group B compared to the group A (p
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