Sphingomonadaceae: Protective against breast cancer?

Autor: Ebidor Ufoumanefe Lawani-Luwaji, Tolulope Alade
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Bulletin of the National Research Centre, Vol 44, Iss 1, Pp 1-5 (2020)
Druh dokumentu: article
ISSN: 2522-8307
66477697
DOI: 10.1186/s42269-020-00447-0
Popis: Abstract Background Breast cancer is the most common malignancy and one of the leading causes of cancer-linked deaths in women. The development of the mammary gland is regulated by oestrogen whose activities have also been linked with various diseases including breast cancer. Research has shown that host–microbiota relationship plays a role in human health and disease, so we investigated the association between breast microbiota and breast cancer. A search of the literature was conducted using search tools such as Google Scholar, PubMed, EBSCO and Cochrane library with the terms breast cancer, breast microbiota, microbiome and dysbiosis. A further search included Sphingomonas, Sphingobium yanoikuyae and oestrogen. The search terms were combined in original forms to get relevant studies related to the subject under review. All articles written in English were included and publication dates were not limited. Conclusion Taken together, the studies show that Sphingobium yanoikuyae might have a protective role in breast cancer, especially oestrogen positive, and highlights the need for further investigation into the use of the bacteria for prevention and possibly management of breast cancer.
Databáze: Directory of Open Access Journals
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