A report of two cases of dedifferentiated endometrioid carcinoma: A newly described underrecognized tumor of poor prognosis

Autor:	Anup K Boler, Sana Akhtar, Arghya Bandyopadhyay, Shreosee Roy
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	dedifferentiated endometrial carcinoma dedifferentiated endometrioid carcinoma endometrial carcinoma malignant mixed mullerian tumor undifferentiated carcinoma Pathology RB1-214 Microbiology QR1-502
Zdroj:	Indian Journal of Pathology and Microbiology, Vol 63, Iss 5, Pp 91-93 (2020)
Druh dokumentu:	article
ISSN:	0377-4929
DOI:	10.4103/IJPM.IJPM_23_19
Popis:	Dedifferentiated endometrioid carcinoma or dedifferentiated endometrioid adenocarcinoma (DEAC) is defined by the presence of undifferentiated carcinoma with endometrioid carcinoma. Undifferentiated component can be misinterpreted as solid component of high-grade endometrioid carcinoma or sarcomatous component of malignant mixed mullerian tumor. We present two cases of DEAC. Two postmenopausal women underwent hysterectomy for vaginal bleeding. Microscopically, sections from the endometrial tumors showed a biphasic growth consisting of an undifferentiated component and a glandular component with sharp transition between the two components. The undifferentiated component showed focal positivity for cytokeratin and vimentin, while glandular component was diffusely positive for cytokeratin and negative for vimentin expression.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/bd0d49d425e54809a481f3c27f56279f Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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