Scleroderma diabeticorum: a case report

Autor: I. U. Wimalasiri, S. Siyambalapitiya
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Sri Lanka Journal of Diabetes Endocrinology and Metabolism, Vol 7, Iss 1, Pp 39-41 (2017)
Druh dokumentu: article
ISSN: 2012-998X
DOI: 10.4038/sjdem.v7i1.7327
Popis: Scleroderma diabeticorum is a rare dermatological condition that is found in patients with poorly controlled long-standing diabetes. This is characterized by symmetrical, wooden non-pitting induration of the neck, and the upper parts of the shoulders and back. Aetiology of the scleroderma diabeticorum is not well understood. However, the hyperglycaemia-related fibroblast proliferation and extra-cellular ground substance formation is thought to be the main reason for the associated skin changes. Treatment of this condition is a challenge. Good glycaemia control has demonstrated partial resolution in some individuals. However, some studies have not shown any improvement with good glycaemic control. Phototherapy with UVA-1, immunosuppressive drugs and frequency modulated electromagnetic neural stimulation (FREMS) have been successful to a reasonable extent in some patients.
Databáze: Directory of Open Access Journals