Pigmented variant of pleomorphic xanthoastrocytoma - A rare long-term epilepsy associated neoplasm

Autor: Rajalakshmi Poyuran, Nirupam Moudgil, Arivazhagan Arimappamagan, Rose D Bharath, Anita Mahadevan
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Indian Journal of Pathology and Microbiology, Vol 62, Iss 3, Pp 445-447 (2019)
Druh dokumentu: article
ISSN: 0377-4929
DOI: 10.4103/IJPM.IJPM_723_18
Popis: Pleomorphic xanthoastrocytoma (PXA) is an uncommon, long-term epilepsy associated tumor of young adults. Its pigmented variant is exceedingly rare, with only five previously reported cases on record. We report the sixth case of pigmented PXA in a 24-year-old lady presenting with long-standing seizures. The MRI revealed a solid cystic lesion located in the right medial temporal lobe. Histopathologically, the superficially located tumor showed typical features of PXA with melanin-laden astrocytic component and was negative for V600E-mutant BRAF. The histogenesis is discussed.
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