Adrenal Venous Sampling for Subtype Diagnosis of Primary Hyperaldosteronism

Autor:	Mitsuhide Naruse, Akiyo Tanabe, Koichi Yamamoto, Hiromi Rakugi, Mitsuhiro Kometani, Takashi Yoneda, Hiroki Kobayashi, Masanori Abe, Youichi Ohno, Nobuya Inagaki, Shoichiro Izawa, Masakatsu Sone
Jazyk:	English<br />Korean
Rok vydání:	2021
Předmět:	aldosterone adrenocorticotropic hormone adenoma catherterization hyperaldosteronism Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Endocrinology and Metabolism, Vol 36, Iss 5, Pp 965-973 (2021)
Druh dokumentu:	article
ISSN:	2093-596X 2093-5978
DOI:	10.3803/EnM.2021.1192
Popis:	Adrenal venous sampling (AVS) is the key procedure for lateralization of primary hyperaldosteronism (PA) before surgery. Identification of the adrenal veins using computed tomography (CT) and intraoperative cortisol assay facilitates the success of catheterization. Although administration of adrenocorticotropic hormone (ACTH) has benefits such as improving the success rate, some unilateral cases could be falsely diagnosed as bilateral. Selectivity index of 5 with ACTH stimulation to assess the selectivity of catheterization and lateralization index (LI) >4 with ACTH stimulation for unilateral diagnosis is used in many centers. Co-secretion of cortisol from the tumor potentially affects the lateralization by the LI. Patients aged
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/bce7f047585e4f91a821d18b22885574 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF