Kaposi’s sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs

Autor: James C. Murphy, Elena M. Harrington, Sophie Schumann, Elton J. R. Vasconcelos, Timothy J. Mottram, Katherine L. Harper, Julie L. Aspden, Adrian Whitehouse
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-35914-5
Popis: Viruses rely on the translational machinery of the host cell to synthesis viral proteins. We show that KSHV manipulates the composition of host cell ribosomes creating a specialised ribosome to specifically translate viral mRNAs.
Databáze: Directory of Open Access Journals