Intensive blood pressure control in isolated systolic hypertension: a post hoc analysis of a cluster randomized trialResearch in context

Autor: Chang Wang, Songyue Liu, Wei Miao, Ning Ye, Ziyi Xie, Lixia Qiao, Nanxiang Ouyang, Yangzhi Yin, Yingxian Sun, Guozhe Sun
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Lancet Regional Health. Western Pacific, Vol 48, Iss , Pp 101127- (2024)
Druh dokumentu: article
ISSN: 2666-6065
DOI: 10.1016/j.lanwpc.2024.101127
Popis: Summary: Background: The isolated systolic hypertension (ISH) is of high prevalence, with a relatively poor prognosis. However, there is still no direct evidence to demonstrate the benefits of intensive blood pressure (BP) control among these patients. We aimed to evaluate intensive BP control with the target of 0.05 for all interaction test). The incidences of symptomatic hypotension, syncope injurious falls and renal outcomes did not differ between the two groups, even though hypotension was increased in intervention group (RR:1.71; 95% CI: 1.28–2.28; P
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