Further intracellular proteins and signaling pathways regulated by angiotensin-(1–7) in human endothelial cells

Autor: Christian Meinert, Franziska Kohse, Ilka Böhme, Florian Gembardt, Anja Tetzner, Thomas Wieland, Barry Greenberg, Thomas Walther
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Data in Brief, Vol 10, Iss C, Pp 354-363 (2017)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2016.12.004
Popis: In 2016, Meinert et al. (doi: 10.1016/j.jprot.2015.09.020) published the first 25 proteins in a protein array regulated in Human Umbilical Vein Endothelial Cells (HUVEC) by the heptapeptide angiotensin (Ang)-(1–7) and the first 10 intracellular signaling cascades at different time points. This supporting data article shows further proteins and pathways stimulated by Ang-(1–7) in human endothelial cells at time points of 1 h, 3 h, 6 h, and 9 h. HUVECs were stimulated with Ang-(1–7), and regulated proteins were identified via antibody microarray. Bioinformatics software IPA was used for association of regulated proteins to metabolic pathways.
Databáze: Directory of Open Access Journals