| Autor: |
Julie Goswami, Taleen A. MacArthur, Cillian R. Mahony, Joseph Immermann, Michael J. Ferrara, Denise B. Klinkner, Stephanie F. Polites, Beth A. Ballinger, Rosemary A. Kozar, Jing-Fei Dong, Matthew T. Auton, Grant Spears, Kent R. Bailey, Donald H. Jenkins, Myung S. Park |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Surgery in Practice and Science, Vol 10, Iss , Pp 100117- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-2620 |
| DOI: |
10.1016/j.sipas.2022.100117 |
| Popis: |
Background: Injured patients have early changes to normal coagulation that can impact long term risk for thrombotic complications. There is little known about how age impacts biomarkers of coagulation after traumatic injury. In this pilot study, we aimed to characterize thrombin generation kinetics, a known predictor of venous thromboembolism, in trauma patients across the age spectrum. Methods: Citrated plasma samples were collected from 174 trauma patients (3–94 years old). Thrombin generation kinetics were measured using calibrated automated thrombogram (CAT) and expressed as lag time (LT – minutes) and time to peak (ttPeak – minutes). Kruskal-Wallis, Spearman correlation, and multivariable regression analysis were carried out. Data in median and quartiles [Q1, Q3]. P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
