Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum
| Autor: | Larisse Rayanne Miranda de Melo, Heleni Aires Clemente, Dalila Fernandes Bezerra, Raquel Costa Silva Dantas, Héryka Myrna Maia Ramalho, Roberto Dimenstein |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Jornal de Pediatria, Vol 93, Iss 1, Pp 40-46 (2017) |
| Druh dokumentu: | article |
| ISSN: | 0021-7557 17072964 |
| DOI: | 10.1016/j.jped.2016.03.007 |
| Popis: | Objective: To evaluate the effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum and its supply to the newborn. Method: This randomized clinical trial enrolled 99 healthy adult pregnant women; of these, 39 were assigned to the control group and 60 to the supplemented group. After an overnight fast, 5 mL of blood and 2 mL of colostrum were collected. After the first sampling (0 h milk), the supplemented group received 400 IU of supplementary vitamin E. Another 2 mL milk aliquot was collected in both groups 24 h after supplementation (24 h milk). The samples were analyzed by high-performance liquid chromatography. The α-tocopherol content provided by colostrum was calculated by considering a daily intake of 396 mL of milk and comparing the resulting value to the recommended daily intake for infants aged 0–6 months (4 mg/day). Results: The initial mean concentration of α-tocopherol in colostrum was 1509.3 ± 793.7 μg/dL in the control group and 1452.9 ± 808.6 μg/dL in the supplemented group. After 24 h, the mean α-tocopherol concentration was 1650.6 ± 968.7 μg/dL in the control group (p > 0.05) and 2346.9 ± 1203.2 μg/dL in the supplemented group (p 0,05), já no grupo suplementado a concentração média foi 2346,9 ± 1203,2 μg/dL (p |
| Databáze: | Directory of Open Access Journals |
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