Heterogeneity of Monosymptomatic Resting Tremor in a Prospective Study: Clinical Features, Electrophysiological Test, and Dopamine Transporter Positron Emission Tomography

Autor: Hua-Guang Zheng, Rong Zhang, Xin Li, Fang-Fei Li, Ya-Chen Wang, Xue-Mei Wang, Ling-Long Lu, Tao Feng
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Chinese Medical Journal, Vol 128, Iss 13, Pp 1765-1771 (2015)
Druh dokumentu: article
ISSN: 0366-6999
DOI: 10.4103/0366-6999.159352
Popis: Background: The relationship between monosymptomatic resting tremor (mRT) and Parkinson′s disease (PD) remains controversial. In this study, we aimed to assess the function of presynaptic dopaminergic neurons in patients with mRT by dopamine transporter positron emission tomography (DAT-PET) and to evaluate the utility of clinical features or electrophysiological studies in differential diagnosis. Methods: Thirty-three consecutive patients with mRT were enrolled prospectively. The Unified Parkinson′s Disease Rating Scale and electromyography were tested before DAT-PET. Striatal asymmetry index (SAI) was calculated, and a normal DAT-PET was defined as a SAI of
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