Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm

Autor: David B. Carroll, Conrad Myler, Natthapol Songdej, Khaled Sedeek, Dmitri Bezinover
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Case Reports in Anesthesiology, Vol 2020 (2020)
Druh dokumentu: article
ISSN: 2090-6382
2090-6390
DOI: 10.1155/2020/8892225
Popis: Factor XIII (FXIII) deficiency is a rare coagulation defect that can be associated with significant bleeding. A 28-year-old pregnant woman, with a history of hemorrhagic stroke secondary to severe congenital FXIII deficiency, presented in active labor requesting an epidural. Factor XIII levels had been monitored throughout her pregnancy and treated with intermittent factor XIII infusions to maintain factor levels above 30% of normal. After careful multidisciplinary peripartum evaluation and FXIII replacement, neuraxial analgesia was performed without complication. Neuraxial analgesia can be performed without complication in patients with FXIII deficiency if FXIII levels are carefully managed and no other coagulopathy exists.
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