Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases

Autor: Qiuyang Zhang, Qing Liu, Siguo Feng, Xiumiao Li, Qin Jiang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Biomolecules, Vol 14, Iss 3, p 328 (2024)
Druh dokumentu: article
ISSN: 2218-273X
DOI: 10.3390/biom14030328
Popis: Ocular neovascularization can impair vision and threaten patients’ quality of life. However, the underlying mechanism is far from transparent. In all mammals, macrophages are a population of cells playing pivotal roles in the innate immune system and the first line of defense against pathogens. Therefore, it has been speculated that the disfunction of macrophage homeostasis is involved in the development of ocular vascular diseases. Moreover, various studies have found that non-coding RNAs (ncRNAs) regulate macrophage homeostasis. This study reviewed past studies of the regulatory roles of ncRNAs in macrophage homeostasis in ocular vascular diseases.
Databáze: Directory of Open Access Journals
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