| Autor: |
Nader J. Al‐Shakarchi, Jamie S.Y. Ho, Jonathan J.H. Bray, Fabrizio D'Ascenzo, Edward Duffy, Jack Hewett, Divine Adegbie, Faizullah Khan, Niraj S. Kumar, Neal Patel, Mahmood Ahmad, Amitava Banerjee, Ikram Haq, Rui Providencia |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
ESC Heart Failure, Vol 11, Iss 5, Pp 2616-2626 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2055-5822 |
| DOI: |
10.1002/ehf2.14835 |
| Popis: |
Abstract Aims The viability of cardiac resynchronization therapy (CRT) in inotrope‐dependent heart failure (HF) has been a matter of debate. Methods and results We searched Medline, EMBASE, Scopus, and the Cochrane Library until 31 December 2022. Studies were included if (i) HF patients required inotropic support at CRT implantation; (ii) patients were ≥18 years old; and (iii) they provided a clear definition of ‘inotrope dependence’ or ‘inability to wean’. A meta‐analysis was performed in R (Version 3.5.1). Nineteen studies comprising 386 inotrope‐dependent HF patients who received CRT (mean age 64.4 years, 76.9% male) were included. A large majority survived until discharge at 91.1% [95% confidence interval (CI): 81.2% to 97.6%], 89.3% were weaned off inotropes (95% CI: 77.6% to 97.0%), and mean discharge time post‐CRT was 7.8 days (95% CI: 3.9 to 11.7). After 1 year of follow‐up, 69.7% survived (95% CI: 58.4% to 79.8%). During follow‐up, the mean number of HF hospitalizations was reduced by 1.87 (95% CI: 1.04 to 2.70, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Plný text